ESR1 Amplification is Rare in Breast Cancer and is Associated with High Grade and High Proliferation: A Multiplex Ligation-Dependent Probe Amplification Study

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Background: Expression of estrogen receptor alpha (ERα) is predictive for endocrine therapy response and an important prognostic factor in breast cancer. Overexpression of ERα can be caused by estrogen receptor 1 (ESR1) gene amplification and was originally reported to be a frequent event associated...

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Detalles Bibliográficos
Autores principales: Moelans, Cathy B., Monsuur, Hanneke N., de Pinth, Johannes H., Radersma, Remco D., de Weger, Roel A., van Diest, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2010
Materias:
Other
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605667/
https://www.ncbi.nlm.nih.gov/pubmed/20966540
http://dx.doi.org/10.3233/ACP-CLO-2010-0527
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