Cargando…

Pathways and Barriers for Ion Translocation through the 5-HT(3)A Receptor Channel

Pentameric ligand gated ion channels (pLGICs) are ionotropic receptors that mediate fast intercellular communications at synaptic level and include either cation selective (e.g., nAChR and 5-HT(3)) or anion selective (e.g., GlyR, GABA(A) and GluCl) membrane channels. Among others, 5-HT(3) is one of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Di Maio, Danilo, Chandramouli, Balasubramanian, Brancato, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605793/ https://www.ncbi.nlm.nih.gov/pubmed/26465896 http://dx.doi.org/10.1371/journal.pone.0140258

Ejemplares similares

Breaking the Hydrophobicity of the MscL Pore: Insights into a Charge-Induced Gating Mechanism
por: Chandramouli, Balasubramanian, et al.
Publicado: (2015)

Understanding the role of dynamics in the iron sulfur cluster molecular machine
por: di Maio, Danilo, et al.
Publicado: (2017)

5-HT3 receptor ion size selectivity is a property of the transmembrane channel, not the cytoplasmic vestibule portals
por: McKinnon, Nicole K., et al.
Publicado: (2011)

Ion Conductivity of the Bacterial Translocation Channel SecYEG Engaged in Translocation
por: Knyazev, Denis G., et al.
Publicado: (2014)

Allosteric Inhibition of Serotonin 5-HT(7) Receptors by Zinc Ions
por: Satała, Grzegorz, et al.
Publicado: (2017)

A single channel mutation alters agonist efficacy at 5-HT(3)A and 5-HT(3)AB receptors
por: Thompson, A J, et al.
Publicado: (2013)

Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT(3) receptor via a common vestibule site
por: Brams, Marijke, et al.
Publicado: (2020)

Induced Polarization in Molecular Dynamics Simulations of the 5-HT(3) Receptor Channel
por: Klesse, Gianni, et al.
Publicado: (2020)

Mobility of Lower MA-Helices for Ion Conduction through Lateral Portals in 5-HT(3A) Receptors
por: Stuebler, Antonia G., et al.
Publicado: (2020)

Distribution of 5-HT(3), 5-HT(4), and 5-HT(7) Receptors Along the Human Colon
por: Yaakob, Nor S, et al.
Publicado: (2015)

Differential Control by 5‐HT and 5‐HT1A, 2A, 2C Receptors of Phasic and Tonic GABAA Inhibition in the Visual Thalamus
por: Crunelli, Vincenzo, et al.
Publicado: (2015)

5-HT(3) Receptors
por: Lummis, Sarah C. R.
Publicado: (2012)

Cardiac Roles of Serotonin (5-HT) and 5-HT-Receptors in Health and Disease
por: Neumann, Joachim, et al.
Publicado: (2023)

Review: 5-HT(1), 5-HT(2), 5-HT(3) and 5-HT(7) Receptors and their Role in the Modulation of Pain Response in the Central Nervous System
por: Cortes-Altamirano, Jose Luis, et al.
Publicado: (2018)

Role for serotonin2A (5-HT2A) and 2C (5-HT2C) receptors in experimental absence seizures
por: Venzi, Marcello, et al.
Publicado: (2016)

Examination of the mechanism of Piezo ion channel in 5-HT synthesis in the enterochromaffin cell and its association with gut motility
por: Zhu, Zhenya, et al.
Publicado: (2023)

Human 5–HT(4) and 5–HT(7) Receptor Splice Variants: Are they Important?
por: Coupar, Ian M, et al.
Publicado: (2007)

Discriminating between 5-HT(3)A and 5-HT(3)AB receptors
por: Thompson, AJ, et al.
Publicado: (2013)

Conservation of 5-HT(1A) receptor-mediated autoinhibition of serotonin (5-HT) neurons in mice with altered 5-HT homeostasis
por: Araragi, Naozumi, et al.
Publicado: (2013)

The role of 5-HT receptors in depression
por: Yohn, Christine N., et al.
Publicado: (2017)

5-HT Receptors and Temperature Homeostasis
por: Voronova, Irina P.
Publicado: (2021)

Activation of 5-HT(2A/C) Receptors Counteracts 5-HT(1A) Regulation of N-Methyl-D-aspartate Receptor Channels in Pyramidal Neurons of Prefrontal Cortex
por: Yuen, Eunice Y., et al.
Publicado: (2008)

Existence of Brain 5-HT1A–5-HT2A Isoreceptor Complexes with Antagonistic Allosteric Receptor–Receptor Interactions Regulating 5-HT1A Receptor Recognition
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2017)

5-HT(2A) and 5-HT(2C) receptors as hypothalamic targets of developmental programming in male rats
por: Martin-Gronert, Malgorzata S., et al.
Publicado: (2016)

Pharmacological Characterization of 5-HT(1A) Autoreceptor-Coupled GIRK Channels in Rat Dorsal Raphe 5-HT Neurons
por: Montalbano, Alberto, et al.
Publicado: (2015)

Ion selectivity of the anthrax toxin channel and its effect on protein translocation
por: Schiffmiller, Aviva, et al.
Publicado: (2015)

Constitutively Active 5-HT Receptors: An Explanation of How 5-HT Antagonists Inhibit Gut Motility in Species Where 5-HT is Not an Enteric Neurotransmitter?
por: Spencer, Nick J.
Publicado: (2015)

Regulatory mechanism of CCN2 production by serotonin (5-HT) via 5-HT(2A) and 5-HT(2B) receptors in chondrocytes
por: Hori, Ayaka, et al.
Publicado: (2017)

Rings of Charge within the Extracellular Vestibule Influence Ion Permeation of the 5-HT(3)A Receptor
por: Livesey, Matthew R., et al.
Publicado: (2011)

Biophysical validation of serotonin 5-HT(2A) and 5-HT(2C) receptor interaction
por: Felsing, Daniel E., et al.
Publicado: (2018)

Serotoninergic neurons and 5-HT receptors in the CNS
Publicado: (2000)

Central and peripheral 5-HT3 receptors
Publicado: (1992)

5-HT(6 )receptors and Alzheimer's disease
por: Ramírez, María Javier
Publicado: (2013)

5-HT Receptors and the Development of New Antidepressants
por: Ślifirski, Grzegorz, et al.
Publicado: (2021)

5-HT(2A), 5-HT(1B/D), 5HT(3) and 5-HT(7) receptors as mediators of serotonin-induced direct contractile response of bovine airway smooth muscle
por: Da Costa Guevara, Darwin, et al.
Publicado: (2021)

Sizing the Protein Translocation Pathway of Colicin Ia Channels
por: Kienker, Paul K., et al.
Publicado: (2003)

Identification of 5-HT(2A) Receptor Signaling Pathways Responsible for Psychedelic Potential
por: Wallach, Jason, et al.
Publicado: (2023)

Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H(4) and the ion channel serotonin 5-HT(3A)
por: Verheij, Mark H.P., et al.
Publicado: (2011)

Effects of Acute MDMA Intoxication on Mood and Impulsivity: Role of the 5-HT(2) and 5-HT(1) Receptors
por: van Wel, Janelle H. P., et al.
Publicado: (2012)

The influence of resonant channels on sub-barrier heavy-ion fusion
por: Hussein, M S, et al.
Publicado: (1995)

Cannot write session to /tmp/vufind_sessions/sess_4n13m615p5phjt1jlshjfv7u4v