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Global quantitative analysis of phosphorylation underlying phencyclidine signaling and sensorimotor gating in the prefrontal cortex

Prepulse inhibition (PPI) is an example of sensorimotor gating and deficits in PPI have been demonstrated in schizophrenia patients. Phencyclidine (PCP) suppression of PPI in animals has been studied to elucidate the pathological elements of schizophrenia. However, the molecular mechanisms underlyin...

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Detalles Bibliográficos
Autores principales: McClatchy, Daniel B., Savas, Jeffrey N., Martínez-Bartolomé, Salvador, Park, Sung Kyu, Maher, Pamela, Powell, Susan B., Yates, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605830/
https://www.ncbi.nlm.nih.gov/pubmed/25869802
http://dx.doi.org/10.1038/mp.2015.41