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Full factorial design for optimization, development and validation of HPLC method to determine valsartan in nanoparticles
High performance liquid chromatographic method was optimized, developed and validated as per the ICH guidelines. In this study the 20 mM ammonium formate and acetonitrile in the 57:43 ratio were used as mobile phase for the analysis of valsartan. Full factorial design was used to optimize the effect...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605903/ https://www.ncbi.nlm.nih.gov/pubmed/26594122 http://dx.doi.org/10.1016/j.jsps.2015.02.001 |