The PI3K regulatory subunit gene PIK3R1 is under direct control of androgens and repressed in prostate cancer cells

Androgen receptor (AR) signalling and the PI3K pathway mediate survival signals in prostate cancer, and have been shown to regulate each other by reciprocal negative feedback, such that inhibition of one activates the other. Understanding the reciprocal regulation of these pathways is important for...

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Detalles Bibliográficos
Autores principales: Munkley, Jennifer, Livermore, Karen E., McClurg, Urszula L., Kalna, Gabriela, Knight, Bridget, McCullagh, Paul, McGrath, John, Crundwell, Malcolm, Leung, Hing Y., Robson, Craig N., Harries, Lorna W., Rajan, Prabhakar, Elliott, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606009/
https://www.ncbi.nlm.nih.gov/pubmed/26501081

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