The Insulin/IGF System in Colorectal Cancer Development and Resistance to Therapy

The insulin/insulin-like growth factor (IGF) system is a major determinant in the pathogenesis and progression of colorectal cancer (CRC). Indeed, several components of this signaling network, including insulin, IGF-1, IGF-2, the IGF-binding proteins, the insulin receptor (IR), the IGF-1 receptor (I...

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Detalles Bibliográficos
Autores principales: Vigneri, Paolo Giovanni, Tirrò, Elena, Pennisi, Maria Stella, Massimino, Michele, Stella, Stefania, Romano, Chiara, Manzella, Livia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606066/
https://www.ncbi.nlm.nih.gov/pubmed/26528439
http://dx.doi.org/10.3389/fonc.2015.00230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606066/
https://www.ncbi.nlm.nih.gov/pubmed/26528439
http://dx.doi.org/10.3389/fonc.2015.00230

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