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The Insulin/IGF System in Colorectal Cancer Development and Resistance to Therapy
The insulin/insulin-like growth factor (IGF) system is a major determinant in the pathogenesis and progression of colorectal cancer (CRC). Indeed, several components of this signaling network, including insulin, IGF-1, IGF-2, the IGF-binding proteins, the insulin receptor (IR), the IGF-1 receptor (I...
Autores principales: | Vigneri, Paolo Giovanni, Tirrò, Elena, Pennisi, Maria Stella, Massimino, Michele, Stella, Stefania, Romano, Chiara, Manzella, Livia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606066/ https://www.ncbi.nlm.nih.gov/pubmed/26528439 http://dx.doi.org/10.3389/fonc.2015.00230 |
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