Acute Hemoperitoneum after Administration of Prostaglandin E(2) for Induction of Labour

Prostaglandin E(2) is widely used in obstetrics and is thought to be relatively safe for cervical ripening and induction of labour. Here we present a case in which acute hemoperitoneum was observed after administration of prostaglandin E(2) in a pregnant woman. The patient had a history of endometriosis, and a severe pelvic adhesion (ASRM stage IV) was found during her last laparoscopic surgery 3 years previously. In cases with endometriosis, use of prostaglandin E(2) for induction of labour in pregnant women must be done cautiously.