Cargando…

Uncovering the dual role of RHAMM as an HA receptor and a regulator of CD44 expression in RHAMM-expressing mesenchymal progenitor cells

The interaction of hyaluronan (HA) with mesenchymal progenitor cells impacts trafficking and fate after tissue colonization during wound repair and these events contribute to diseases such as cancer. How this interaction occurs is poorly understood. Using 10T½ cells as a mesenchymal progenitor model...

Descripción completa

Detalles Bibliográficos
Autores principales:	Veiseh, Mandana, Leith, Sean J., Tolg, Cornelia, Elhayek, Sallie S., Bahrami, S. Bahram, Collis, Lisa, Hamilton, Sara, McCarthy, James B., Bissell, Mina J., Turley, Eva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606125/ https://www.ncbi.nlm.nih.gov/pubmed/26528478 http://dx.doi.org/10.3389/fcell.2015.00063

Ejemplares similares

Hyaluronan and RHAMM in Wound Repair and the “Cancerization” of Stromal Tissues
por: Tolg, Cornelia, et al.
Publicado: (2014)

RHAMM Is a Multifunctional Protein That Regulates Cancer Progression
por: Messam, Britney J., et al.
Publicado: (2021)

Rhamm(−/−) fibroblasts are defective in CD44-mediated ERK1,2 motogenic signaling, leading to defective skin wound repair
por: Tolg, Cornelia, et al.
Publicado: (2006)

“RHAMM knockout” mice express a truncated RHAMM protein that promotes pancreatic cancer progression with dysfunctional p53
por: Chen, Xiang, et al.
Publicado: (2022)

Increased RHAMM expression relates to ovarian cancer progression
por: Buttermore, Stephanie T., et al.
Publicado: (2017)

RHAMM regulates MMTV-PyMT-induced lung metastasis by connecting STING-dependent DNA damage sensing to interferon/STAT1 pro-apoptosis signaling
por: Tolg, Cornelia, et al.
Publicado: (2023)

RHAMM Expression in the Rat Endometrium during the Estrous Cycle and following Implantation
por: Ozbilgin, Kemal, et al.
Publicado: (2012)

RHAMM deficiency disrupts folliculogenesis resulting in female hypofertility
por: Li, Huaibiao, et al.
Publicado: (2015)

The role of RHAMM in cancer: Exposing novel therapeutic vulnerabilities
por: Hinneh, Josephine A., et al.
Publicado: (2022)

The Roles of Hyaluronan/RHAMM/CD44 and Their Respective Interactions along the Insidious Pathways of Fibrosarcoma Progression
por: Nikitovic, Dragana, et al.
Publicado: (2013)

Interactions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and Cancer
por: Misra, Suniti, et al.
Publicado: (2015)

Function and clinical relevance of RHAMM isoforms in pancreatic tumor progression
por: Choi, Soyoung, et al.
Publicado: (2019)

Hyaluronan (HA) Interacting Proteins RHAMM and Hyaluronidase Impact Prostate Cancer Cell Behavior and Invadopodia Formation in 3D HA-Based Hydrogels
por: Gurski, Lisa A., et al.
Publicado: (2012)

Editorial: Interaction Between Hyaluronic Acid and Its Receptors (CD44, RHAMM) Regulates the Activity of Inflammation and Cancer
por: Naor, David
Publicado: (2016)

CD44 and RHAMM are essential for rapid growth of bladder cancer driven by loss of Glycogen Debranching Enzyme (AGL)
por: Oldenburg, Darby, et al.
Publicado: (2016)

Triptolide suppresses the in vitro and in vivo growth of lung cancer cells by targeting hyaluronan-CD44/RHAMM signaling
por: Song, Jung Min, et al.
Publicado: (2017)

RHAMM marks proliferative subpopulation of human colorectal cancer stem cells
por: Nakano, Michitaka, et al.
Publicado: (2023)

Antitumor effect of 4MU on glioblastoma cells is mediated by senescence induction and CD44, RHAMM and p-ERK modulation
por: Pibuel, Matías Arturo, et al.
Publicado: (2021)

Tumor-Tissue Expression of the Hyaluronic Acid Receptor RHAMM Predicts Histological Transformation in Follicular Lymphoma Patients
por: Enemark, Marie Beck, et al.
Publicado: (2022)

RHAMM splice variants confer radiosensitivity in human breast cancer cell lines
por: Schütze, Alexandra, et al.
Publicado: (2016)

RHAMM induces progression of rheumatoid arthritis by enhancing the functions of fibroblast-like synoviocytes
por: Wu, Jing, et al.
Publicado: (2018)

Soluble hyaluronan receptor RHAMM induces mitotic arrest by suppressing Cdc2 and cyclin B1 expression
Publicado: (1996)

The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells
por: Willemen, Yannick, et al.
Publicado: (2016)

TGF-beta 1 stimulation of cell locomotion utilizes the hyaluronan receptor RHAMM and hyaluronan
Publicado: (1993)

The hyaluronan-mediated motility receptor RHAMM promotes growth, invasiveness and dissemination of colorectal cancer
por: Mele, Valentina, et al.
Publicado: (2017)

Hyaluronan and the hyaluronan receptor RHAMM promote focal adhesion turnover and transient tyrosine kinase activity
Publicado: (1994)

The Impact of the Receptor of Hyaluronan-Mediated Motility (RHAMM) on Human Urothelial Transitional Cell Cancer of the Bladder
por: Niedworok, Christian, et al.
Publicado: (2013)

Emodin regulates cell cycle of non-small lung cancer (NSCLC) cells through hyaluronan synthase 2 (HA2)-HA-CD44/receptor for hyaluronic acid-mediated motility (RHAMM) interaction-dependent signaling pathway
por: Li, Mingzhu, et al.
Publicado: (2021)

Expression of the receptor for hyaluronic acid mediated motility (RHAMM) is associated with poor prognosis and metastasis in non-small cell lung carcinoma
por: Wang, Dunrui, et al.
Publicado: (2016)

Redox Responsive Hyaluronic Acid Nanogels for Treating RHAMM (CD168) Over-expressive Cancer, both Primary and Metastatic Tumors
por: Yang, Chenchen, et al.
Publicado: (2017)

Immune Responses to RHAMM in Patients with Acute Myeloid Leukemia after Chemotherapy and Allogeneic Stem Cell Transplantation
por: Casalegno-Garduño, R., et al.
Publicado: (2012)

The Cytoskeletal Protein RHAMM and ERK1/2 Activity Maintain the Pluripotency of Murine Embryonic Stem Cells
por: Jiang, Jihong, et al.
Publicado: (2013)

Immunohistochemical analysis of RHAMM expression in normal and neoplastic human tissues: a cell cycle protein with distinctive expression in mitotic cells and testicular germ cells
por: Chen, Yao-Tseng, et al.
Publicado: (2018)

Balancing Thymocyte Adhesion and Motility: A Functional Linkage Between β1 Lntegrins and The Motility Receptor RHAMM
por: Gares, Sheryl L., et al.
Publicado: (2000)

Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer
por: Maxwell, Christopher A., et al.
Publicado: (2011)

RHAMM(B)-mediated bifunctional nanotherapy targeting Bcl-xL and mitochondria for pancreatic neuroendocrine tumor treatment
por: Chen, Xiang, et al.
Publicado: (2021)

Changes in Hyaluronan Metabolism and RHAMM Receptor Expression Accompany Formation of Complicated Carotid Lesions and May be Pro-Angiogenic Mediators of Intimal Neovessel Growth
por: Krupinski, Jerzy, et al.
Publicado: (2008)

Rhosin Suppressed Tumor Cell Metastasis through Inhibition of Rho/YAP Pathway and Expression of RHAMM and CXCR4 in Melanoma and Breast Cancer Cells
por: Tsubaki, Masanobu, et al.
Publicado: (2021)

Hyaluronic acid enhances cell migration and invasion via the YAP1/TAZ-RHAMM axis in malignant pleural mesothelioma
por: Shigeeda, Wataru, et al.
Publicado: (2017)

The Pro-fibrotic Response of Mesenchymal Leader Cells to Lens Wounding Involves Hyaluronic Acid, Its Receptor RHAMM, and Vimentin
por: Menko, A. Sue, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_b2o072kgl3kjs2ep79auccekbn