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Effects of the Variation in Brain Tissue Mechanical Properties on the Intracranial Response of a 6-Year-Old Child

Brain tissue mechanical properties are of importance to investigate child head injury using finite element (FE) method. However, these properties used in child head FE model normally vary in a large range in published literatures because of the insufficient child cadaver experiments. In this work, a...

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Detalles Bibliográficos
Autores principales: Cui, Shihai, Li, Haiyan, Li, Xiangnan, Ruan, Jesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606192/
https://www.ncbi.nlm.nih.gov/pubmed/26495031
http://dx.doi.org/10.1155/2015/529729
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author Cui, Shihai
Li, Haiyan
Li, Xiangnan
Ruan, Jesse
author_facet Cui, Shihai
Li, Haiyan
Li, Xiangnan
Ruan, Jesse
author_sort Cui, Shihai
collection PubMed
description Brain tissue mechanical properties are of importance to investigate child head injury using finite element (FE) method. However, these properties used in child head FE model normally vary in a large range in published literatures because of the insufficient child cadaver experiments. In this work, a head FE model with detailed anatomical structures is developed from the computed tomography (CT) data of a 6-year-old healthy child head. The effects of brain tissue mechanical properties on traumatic brain response are also analyzed by reconstruction of a head impact on engine hood according to Euro-NCAP testing regulation using FE method. The result showed that the variations of brain tissue mechanical parameters in linear viscoelastic constitutive model had different influences on the intracranial response. Furthermore, the opposite trend was obtained in the predicted shear stress and shear strain of brain tissues caused by the variations of mentioned parameters.
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spelling pubmed-46061922015-10-22 Effects of the Variation in Brain Tissue Mechanical Properties on the Intracranial Response of a 6-Year-Old Child Cui, Shihai Li, Haiyan Li, Xiangnan Ruan, Jesse Comput Math Methods Med Research Article Brain tissue mechanical properties are of importance to investigate child head injury using finite element (FE) method. However, these properties used in child head FE model normally vary in a large range in published literatures because of the insufficient child cadaver experiments. In this work, a head FE model with detailed anatomical structures is developed from the computed tomography (CT) data of a 6-year-old healthy child head. The effects of brain tissue mechanical properties on traumatic brain response are also analyzed by reconstruction of a head impact on engine hood according to Euro-NCAP testing regulation using FE method. The result showed that the variations of brain tissue mechanical parameters in linear viscoelastic constitutive model had different influences on the intracranial response. Furthermore, the opposite trend was obtained in the predicted shear stress and shear strain of brain tissues caused by the variations of mentioned parameters. Hindawi Publishing Corporation 2015 2015-10-01 /pmc/articles/PMC4606192/ /pubmed/26495031 http://dx.doi.org/10.1155/2015/529729 Text en Copyright © 2015 Shihai Cui et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Cui, Shihai
Li, Haiyan
Li, Xiangnan
Ruan, Jesse
Effects of the Variation in Brain Tissue Mechanical Properties on the Intracranial Response of a 6-Year-Old Child
title Effects of the Variation in Brain Tissue Mechanical Properties on the Intracranial Response of a 6-Year-Old Child
title_full Effects of the Variation in Brain Tissue Mechanical Properties on the Intracranial Response of a 6-Year-Old Child
title_fullStr Effects of the Variation in Brain Tissue Mechanical Properties on the Intracranial Response of a 6-Year-Old Child
title_full_unstemmed Effects of the Variation in Brain Tissue Mechanical Properties on the Intracranial Response of a 6-Year-Old Child
title_short Effects of the Variation in Brain Tissue Mechanical Properties on the Intracranial Response of a 6-Year-Old Child
title_sort effects of the variation in brain tissue mechanical properties on the intracranial response of a 6-year-old child
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606192/
https://www.ncbi.nlm.nih.gov/pubmed/26495031
http://dx.doi.org/10.1155/2015/529729
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