Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury

BACKGROUND: Macrophages play critical roles in liver regeneration, fibrosis development and resolution. They are among the first responders to liver injury and are implicated in orchestrating the fibrogenic response via multiple mechanisms. Macrophages are also intimately associated with the activat...

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Detalles Bibliográficos
Autores principales: Irvine, Katharine M., Clouston, Andrew D., Gadd, Victoria L., Miller, Gregory C., Wong, Weng-Yew, Melino, Michelle, Maradana, Muralidhara Rao, MacDonald, Kelli, Lang, Richard A., Sweet, Matthew J., Blumenthal, Antje, Powell, Elizabeth E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606475/
https://www.ncbi.nlm.nih.gov/pubmed/26473015
http://dx.doi.org/10.1186/s13069-015-0036-7

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