An in vitro assessment of liposomal topotecan simulating metronomic chemotherapy in combination with radiation in tumor-endothelial spheroids

Low dose metronomic chemotherapy (LDMC) refers to prolonged administration of low dose chemotherapy designed to minimize toxicity and target the tumor endothelium, causing tumor growth inhibition. Topotecan (TPT) when administered at its maximum tolerated dose (MTD) is often associated with systemic...

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Detalles Bibliográficos
Autores principales: Jyoti, Amar, Fugit, Kyle D., Sethi, Pallavi, McGarry, Ronald C., Anderson, Bradley D., Upreti, Meenakshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606561/
https://www.ncbi.nlm.nih.gov/pubmed/26468877
http://dx.doi.org/10.1038/srep15236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606561/
https://www.ncbi.nlm.nih.gov/pubmed/26468877
http://dx.doi.org/10.1038/srep15236

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