Plasmacytoid variant of urothelial carcinoma: Diagnostic challenges and role of immunohistochemistry

Plasmacytoid carcinoma of the urinary bladder or plasmacytoid urothelial carcinoma (PUC) is rare and only recently described a histological variant of transitional cell carcinoma. The morphological resemblance of PUC to other malignancies is a source of diagnostic dilemmas and often misdiagnosis. Im...

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Autores principales: Jairajpuri, Zeeba S., Rana, Safia, Ali, Manal Ashraf, Jetley, Sujata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606587/
https://www.ncbi.nlm.nih.gov/pubmed/26539377
http://dx.doi.org/10.4103/2229-516X.165368
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author Jairajpuri, Zeeba S.
Rana, Safia
Ali, Manal Ashraf
Jetley, Sujata
author_facet Jairajpuri, Zeeba S.
Rana, Safia
Ali, Manal Ashraf
Jetley, Sujata
author_sort Jairajpuri, Zeeba S.
collection PubMed
description Plasmacytoid carcinoma of the urinary bladder or plasmacytoid urothelial carcinoma (PUC) is rare and only recently described a histological variant of transitional cell carcinoma. The morphological resemblance of PUC to other malignancies is a source of diagnostic dilemmas and often misdiagnosis. Immunohistochemistry plays a pivotal role in narrowing the differential diagnosis and reaching to a conclusive diagnosis. A diagnosis of PUC usually carries a dismal prognosis. Hence, correct diagnosis is important. We report here a 52-year-old male with a plasmacytoid variant of urothelial carcinoma.
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spelling pubmed-46065872015-11-04 Plasmacytoid variant of urothelial carcinoma: Diagnostic challenges and role of immunohistochemistry Jairajpuri, Zeeba S. Rana, Safia Ali, Manal Ashraf Jetley, Sujata Int J Appl Basic Med Res Case Report Plasmacytoid carcinoma of the urinary bladder or plasmacytoid urothelial carcinoma (PUC) is rare and only recently described a histological variant of transitional cell carcinoma. The morphological resemblance of PUC to other malignancies is a source of diagnostic dilemmas and often misdiagnosis. Immunohistochemistry plays a pivotal role in narrowing the differential diagnosis and reaching to a conclusive diagnosis. A diagnosis of PUC usually carries a dismal prognosis. Hence, correct diagnosis is important. We report here a 52-year-old male with a plasmacytoid variant of urothelial carcinoma. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4606587/ /pubmed/26539377 http://dx.doi.org/10.4103/2229-516X.165368 Text en Copyright: © 2015 International Journal of Applied and Basic Medical Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Jairajpuri, Zeeba S.
Rana, Safia
Ali, Manal Ashraf
Jetley, Sujata
Plasmacytoid variant of urothelial carcinoma: Diagnostic challenges and role of immunohistochemistry
title Plasmacytoid variant of urothelial carcinoma: Diagnostic challenges and role of immunohistochemistry
title_full Plasmacytoid variant of urothelial carcinoma: Diagnostic challenges and role of immunohistochemistry
title_fullStr Plasmacytoid variant of urothelial carcinoma: Diagnostic challenges and role of immunohistochemistry
title_full_unstemmed Plasmacytoid variant of urothelial carcinoma: Diagnostic challenges and role of immunohistochemistry
title_short Plasmacytoid variant of urothelial carcinoma: Diagnostic challenges and role of immunohistochemistry
title_sort plasmacytoid variant of urothelial carcinoma: diagnostic challenges and role of immunohistochemistry
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606587/
https://www.ncbi.nlm.nih.gov/pubmed/26539377
http://dx.doi.org/10.4103/2229-516X.165368
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