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A clinical study on oral lichen planus with special emphasis on hyperpigmentation

BACKGROUND: Oral lichen planus (OLP) is a unique disorder affecting generally the older age group. Numerous studies have been done on various aspects of OLP such as pathogenesis, rate of malignant transformation, etc. However, very few studies are available with respect to clinical features especial...

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Autores principales: Chitturi, Ravi Teja, Sindhuja, Pandian, Parameswar, R. Arjun, Nirmal, Ramdas Madhavan, Reddy, B. Venkat Ramana, Dineshshankar, Janardhanam, Yoithapprabhunath, Thukanayakanpalayam Ragunathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606647/
https://www.ncbi.nlm.nih.gov/pubmed/26538905
http://dx.doi.org/10.4103/0975-7406.163513
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author Chitturi, Ravi Teja
Sindhuja, Pandian
Parameswar, R. Arjun
Nirmal, Ramdas Madhavan
Reddy, B. Venkat Ramana
Dineshshankar, Janardhanam
Yoithapprabhunath, Thukanayakanpalayam Ragunathan
author_facet Chitturi, Ravi Teja
Sindhuja, Pandian
Parameswar, R. Arjun
Nirmal, Ramdas Madhavan
Reddy, B. Venkat Ramana
Dineshshankar, Janardhanam
Yoithapprabhunath, Thukanayakanpalayam Ragunathan
author_sort Chitturi, Ravi Teja
collection PubMed
description BACKGROUND: Oral lichen planus (OLP) is a unique disorder affecting generally the older age group. Numerous studies have been done on various aspects of OLP such as pathogenesis, rate of malignant transformation, etc. However, very few studies are available with respect to clinical features especially association of hyperpigmentation and OLP. This study aims at studying the clinical aspects of OLP and study the association between hyperpigmentation and OLP in a south Indian population. MATERIALS AND METHODS: A total of 58 patients with OLP who attended the outpatient department of our institution were included in the study and a complete history, followed by thorough intraoral examination was done. All the data were recorded and assessed for statistical analysis using SPSS software. RESULTS: We found that the male to female ratio affected with OLP was 1:1 and the most common form of OLP that was seen was the reticular subtype. Also, buccal mucosa was the most common affected site and more than 60% patients had hyperpigmentation associated with the site affected by OLP. We found a statistically significant relation between the reticular type of OLP and the older age group (51–70 years) with hyperpigmentation. CONCLUSION: Although further studies are required to say anything conclusively, post-inflammatory changes occurring the mucosa due to OLP could be a cause for hyperpigmentation in the sites affected.
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spelling pubmed-46066472015-11-04 A clinical study on oral lichen planus with special emphasis on hyperpigmentation Chitturi, Ravi Teja Sindhuja, Pandian Parameswar, R. Arjun Nirmal, Ramdas Madhavan Reddy, B. Venkat Ramana Dineshshankar, Janardhanam Yoithapprabhunath, Thukanayakanpalayam Ragunathan J Pharm Bioallied Sci Dental Science - Original Article BACKGROUND: Oral lichen planus (OLP) is a unique disorder affecting generally the older age group. Numerous studies have been done on various aspects of OLP such as pathogenesis, rate of malignant transformation, etc. However, very few studies are available with respect to clinical features especially association of hyperpigmentation and OLP. This study aims at studying the clinical aspects of OLP and study the association between hyperpigmentation and OLP in a south Indian population. MATERIALS AND METHODS: A total of 58 patients with OLP who attended the outpatient department of our institution were included in the study and a complete history, followed by thorough intraoral examination was done. All the data were recorded and assessed for statistical analysis using SPSS software. RESULTS: We found that the male to female ratio affected with OLP was 1:1 and the most common form of OLP that was seen was the reticular subtype. Also, buccal mucosa was the most common affected site and more than 60% patients had hyperpigmentation associated with the site affected by OLP. We found a statistically significant relation between the reticular type of OLP and the older age group (51–70 years) with hyperpigmentation. CONCLUSION: Although further studies are required to say anything conclusively, post-inflammatory changes occurring the mucosa due to OLP could be a cause for hyperpigmentation in the sites affected. Medknow Publications & Media Pvt Ltd 2015-08 /pmc/articles/PMC4606647/ /pubmed/26538905 http://dx.doi.org/10.4103/0975-7406.163513 Text en Copyright: © Journal of Pharmacy and Bioallied Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms
spellingShingle Dental Science - Original Article
Chitturi, Ravi Teja
Sindhuja, Pandian
Parameswar, R. Arjun
Nirmal, Ramdas Madhavan
Reddy, B. Venkat Ramana
Dineshshankar, Janardhanam
Yoithapprabhunath, Thukanayakanpalayam Ragunathan
A clinical study on oral lichen planus with special emphasis on hyperpigmentation
title A clinical study on oral lichen planus with special emphasis on hyperpigmentation
title_full A clinical study on oral lichen planus with special emphasis on hyperpigmentation
title_fullStr A clinical study on oral lichen planus with special emphasis on hyperpigmentation
title_full_unstemmed A clinical study on oral lichen planus with special emphasis on hyperpigmentation
title_short A clinical study on oral lichen planus with special emphasis on hyperpigmentation
title_sort clinical study on oral lichen planus with special emphasis on hyperpigmentation
topic Dental Science - Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606647/
https://www.ncbi.nlm.nih.gov/pubmed/26538905
http://dx.doi.org/10.4103/0975-7406.163513
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