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The asymmetry of telomere replication contributes to replicative senescence heterogeneity

In eukaryotes, the absence of telomerase results in telomere shortening, eventually leading to replicative senescence, an arrested state that prevents further cell divisions. While replicative senescence is mainly controlled by telomere length, the heterogeneity of its onset is not well understood....

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Detalles Bibliográficos
Autores principales: Bourgeron, Thibault, Xu, Zhou, Doumic, Marie, Teresa Teixeira, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606794/
https://www.ncbi.nlm.nih.gov/pubmed/26468778
http://dx.doi.org/10.1038/srep15326

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