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Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family

Mycobacterium tuberculosis K, a member of the Beijing family, was first identified in 1999 as the most prevalent genotype in South Korea among clinical isolates of M. tuberculosis from high school outbreaks. M. tuberculosis K is an aerobic, non-motile, Gram-positive, and non-spore-forming rod-shaped...

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Autores principales: Han, Seung Jung, Song, Taeksun, Cho, Yong-Joon, Kim, Jong-Seok, Choi, Soo Young, Bang, Hye-Eun, Chun, Jongsik, Bai, Gill-Han, Cho, Sang-Nae, Shin, Sung Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606834/
https://www.ncbi.nlm.nih.gov/pubmed/26473025
http://dx.doi.org/10.1186/s40793-015-0071-4
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author Han, Seung Jung
Song, Taeksun
Cho, Yong-Joon
Kim, Jong-Seok
Choi, Soo Young
Bang, Hye-Eun
Chun, Jongsik
Bai, Gill-Han
Cho, Sang-Nae
Shin, Sung Jae
author_facet Han, Seung Jung
Song, Taeksun
Cho, Yong-Joon
Kim, Jong-Seok
Choi, Soo Young
Bang, Hye-Eun
Chun, Jongsik
Bai, Gill-Han
Cho, Sang-Nae
Shin, Sung Jae
author_sort Han, Seung Jung
collection PubMed
description Mycobacterium tuberculosis K, a member of the Beijing family, was first identified in 1999 as the most prevalent genotype in South Korea among clinical isolates of M. tuberculosis from high school outbreaks. M. tuberculosis K is an aerobic, non-motile, Gram-positive, and non-spore-forming rod-shaped bacillus. A transmission electron microscopy analysis displayed an abundance of lipid bodies in the cytosol. The genome of the M. tuberculosis K strain was sequenced using two independent sequencing methods (Sanger and Illumina). Here, we present the genomic features of the 4,385,518-bp-long complete genome sequence of M. tuberculosis K (one chromosome, no plasmid, and 65.59 % G + C content) and its annotation, which consists of 4194 genes (3447 genes with predicted functions), 48 RNA genes (3 rRNA and 45 tRNA) and 261 genes with peptide signals. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40793-015-0071-4) contains supplementary material, which is available to authorized users.
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spelling pubmed-46068342015-10-16 Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family Han, Seung Jung Song, Taeksun Cho, Yong-Joon Kim, Jong-Seok Choi, Soo Young Bang, Hye-Eun Chun, Jongsik Bai, Gill-Han Cho, Sang-Nae Shin, Sung Jae Stand Genomic Sci Short Genome Report Mycobacterium tuberculosis K, a member of the Beijing family, was first identified in 1999 as the most prevalent genotype in South Korea among clinical isolates of M. tuberculosis from high school outbreaks. M. tuberculosis K is an aerobic, non-motile, Gram-positive, and non-spore-forming rod-shaped bacillus. A transmission electron microscopy analysis displayed an abundance of lipid bodies in the cytosol. The genome of the M. tuberculosis K strain was sequenced using two independent sequencing methods (Sanger and Illumina). Here, we present the genomic features of the 4,385,518-bp-long complete genome sequence of M. tuberculosis K (one chromosome, no plasmid, and 65.59 % G + C content) and its annotation, which consists of 4194 genes (3447 genes with predicted functions), 48 RNA genes (3 rRNA and 45 tRNA) and 261 genes with peptide signals. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40793-015-0071-4) contains supplementary material, which is available to authorized users. BioMed Central 2015-10-14 /pmc/articles/PMC4606834/ /pubmed/26473025 http://dx.doi.org/10.1186/s40793-015-0071-4 Text en © Han et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Short Genome Report
Han, Seung Jung
Song, Taeksun
Cho, Yong-Joon
Kim, Jong-Seok
Choi, Soo Young
Bang, Hye-Eun
Chun, Jongsik
Bai, Gill-Han
Cho, Sang-Nae
Shin, Sung Jae
Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family
title Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family
title_full Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family
title_fullStr Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family
title_full_unstemmed Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family
title_short Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family
title_sort complete genome sequence of mycobacterium tuberculosis k from a korean high school outbreak, belonging to the beijing family
topic Short Genome Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606834/
https://www.ncbi.nlm.nih.gov/pubmed/26473025
http://dx.doi.org/10.1186/s40793-015-0071-4
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