Cargando…
Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family
Mycobacterium tuberculosis K, a member of the Beijing family, was first identified in 1999 as the most prevalent genotype in South Korea among clinical isolates of M. tuberculosis from high school outbreaks. M. tuberculosis K is an aerobic, non-motile, Gram-positive, and non-spore-forming rod-shaped...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606834/ https://www.ncbi.nlm.nih.gov/pubmed/26473025 http://dx.doi.org/10.1186/s40793-015-0071-4 |
_version_ | 1782395432570191872 |
---|---|
author | Han, Seung Jung Song, Taeksun Cho, Yong-Joon Kim, Jong-Seok Choi, Soo Young Bang, Hye-Eun Chun, Jongsik Bai, Gill-Han Cho, Sang-Nae Shin, Sung Jae |
author_facet | Han, Seung Jung Song, Taeksun Cho, Yong-Joon Kim, Jong-Seok Choi, Soo Young Bang, Hye-Eun Chun, Jongsik Bai, Gill-Han Cho, Sang-Nae Shin, Sung Jae |
author_sort | Han, Seung Jung |
collection | PubMed |
description | Mycobacterium tuberculosis K, a member of the Beijing family, was first identified in 1999 as the most prevalent genotype in South Korea among clinical isolates of M. tuberculosis from high school outbreaks. M. tuberculosis K is an aerobic, non-motile, Gram-positive, and non-spore-forming rod-shaped bacillus. A transmission electron microscopy analysis displayed an abundance of lipid bodies in the cytosol. The genome of the M. tuberculosis K strain was sequenced using two independent sequencing methods (Sanger and Illumina). Here, we present the genomic features of the 4,385,518-bp-long complete genome sequence of M. tuberculosis K (one chromosome, no plasmid, and 65.59 % G + C content) and its annotation, which consists of 4194 genes (3447 genes with predicted functions), 48 RNA genes (3 rRNA and 45 tRNA) and 261 genes with peptide signals. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40793-015-0071-4) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-4606834 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-46068342015-10-16 Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family Han, Seung Jung Song, Taeksun Cho, Yong-Joon Kim, Jong-Seok Choi, Soo Young Bang, Hye-Eun Chun, Jongsik Bai, Gill-Han Cho, Sang-Nae Shin, Sung Jae Stand Genomic Sci Short Genome Report Mycobacterium tuberculosis K, a member of the Beijing family, was first identified in 1999 as the most prevalent genotype in South Korea among clinical isolates of M. tuberculosis from high school outbreaks. M. tuberculosis K is an aerobic, non-motile, Gram-positive, and non-spore-forming rod-shaped bacillus. A transmission electron microscopy analysis displayed an abundance of lipid bodies in the cytosol. The genome of the M. tuberculosis K strain was sequenced using two independent sequencing methods (Sanger and Illumina). Here, we present the genomic features of the 4,385,518-bp-long complete genome sequence of M. tuberculosis K (one chromosome, no plasmid, and 65.59 % G + C content) and its annotation, which consists of 4194 genes (3447 genes with predicted functions), 48 RNA genes (3 rRNA and 45 tRNA) and 261 genes with peptide signals. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40793-015-0071-4) contains supplementary material, which is available to authorized users. BioMed Central 2015-10-14 /pmc/articles/PMC4606834/ /pubmed/26473025 http://dx.doi.org/10.1186/s40793-015-0071-4 Text en © Han et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Short Genome Report Han, Seung Jung Song, Taeksun Cho, Yong-Joon Kim, Jong-Seok Choi, Soo Young Bang, Hye-Eun Chun, Jongsik Bai, Gill-Han Cho, Sang-Nae Shin, Sung Jae Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family |
title | Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family |
title_full | Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family |
title_fullStr | Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family |
title_full_unstemmed | Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family |
title_short | Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family |
title_sort | complete genome sequence of mycobacterium tuberculosis k from a korean high school outbreak, belonging to the beijing family |
topic | Short Genome Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606834/ https://www.ncbi.nlm.nih.gov/pubmed/26473025 http://dx.doi.org/10.1186/s40793-015-0071-4 |
work_keys_str_mv | AT hanseungjung completegenomesequenceofmycobacteriumtuberculosiskfromakoreanhighschooloutbreakbelongingtothebeijingfamily AT songtaeksun completegenomesequenceofmycobacteriumtuberculosiskfromakoreanhighschooloutbreakbelongingtothebeijingfamily AT choyongjoon completegenomesequenceofmycobacteriumtuberculosiskfromakoreanhighschooloutbreakbelongingtothebeijingfamily AT kimjongseok completegenomesequenceofmycobacteriumtuberculosiskfromakoreanhighschooloutbreakbelongingtothebeijingfamily AT choisooyoung completegenomesequenceofmycobacteriumtuberculosiskfromakoreanhighschooloutbreakbelongingtothebeijingfamily AT banghyeeun completegenomesequenceofmycobacteriumtuberculosiskfromakoreanhighschooloutbreakbelongingtothebeijingfamily AT chunjongsik completegenomesequenceofmycobacteriumtuberculosiskfromakoreanhighschooloutbreakbelongingtothebeijingfamily AT baigillhan completegenomesequenceofmycobacteriumtuberculosiskfromakoreanhighschooloutbreakbelongingtothebeijingfamily AT chosangnae completegenomesequenceofmycobacteriumtuberculosiskfromakoreanhighschooloutbreakbelongingtothebeijingfamily AT shinsungjae completegenomesequenceofmycobacteriumtuberculosiskfromakoreanhighschooloutbreakbelongingtothebeijingfamily |