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p-STAT6, PU.1, and NF-κB are involved in allergen-induced late-phase airway inflammation in asthma patients

BACKGROUND: Previous in vitro and animal studies demonstrated that transcription factors p-STAT6 and PU.1 are required to induce interleukin (IL)-9 secretion by T helper (Th) 9 cells. It is believed that n factor-kappaB (NF-κB) plays a role in eosinophil survival. The importance of these transcripti...

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Detalles Bibliográficos
Autores principales: Hoppenot, Deimante, Malakauskas, Kestutis, Lavinskiene, Simona, Sakalauskas, Raimundas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606997/
https://www.ncbi.nlm.nih.gov/pubmed/26466682
http://dx.doi.org/10.1186/s12890-015-0119-7