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Fractalkine Signaling Regulates the Inflammatory Response in an α-Synuclein Model of Parkinson Disease
BACKGROUND: Parkinson disease (PD) is a progressive neurodegenerative disorder characterized by loss of dopamine neurons in the substantia nigra pars compacta (SNpc) and widespread aggregates of the protein alpha-synuclein (α-syn). Increasing evidence points to inflammation as a chief mediator; howe...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607155/ https://www.ncbi.nlm.nih.gov/pubmed/26469270 http://dx.doi.org/10.1371/journal.pone.0140566 |