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Gedunin and Azadiradione: Human Pancreatic Alpha-Amylase Inhibiting Limonoids from Neem (Azadirachta indica) as Anti-Diabetic Agents
Human pancreatic α-amylase (HPA) inhibitors offer an effective strategy to lower postprandial hyperglycemia via control of starch breakdown. Limonoids from Azadirachta indica known for their therapeutic potential were screened for pancreatic α-amylase inhibition, a known anti-diabetic target. Studie...
Autores principales: | Ponnusamy, Sudha, Haldar, Saikat, Mulani, Fayaj, Zinjarde, Smita, Thulasiram, Hirekodathakallu, RaviKumar, Ameeta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607367/ https://www.ncbi.nlm.nih.gov/pubmed/26469405 http://dx.doi.org/10.1371/journal.pone.0140113 |
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