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A Novel Dual Expression Platform for High Throughput Functional Screening of Phage Libraries in Product like Format

High throughput screenings of single chain Fv (scFv) antibody phage display libraries are currently done as soluble scFvs produced in E.coli. Due to endotoxin contaminations from bacterial cells these preparations cannot be reliably used in mammalian cell based assays. The monovalent nature and lack...

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Detalles Bibliográficos
Autores principales:	Xiao, Xiaodong, Chen, Yan, Mugabe, Sheila, Gao, Changshou, Tkaczyk, Christine, Mazor, Yariv, Pavlik, Peter, Wu, Herren, Dall’Acqua, William, Chowdhury, Partha Sarathi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607404/ https://www.ncbi.nlm.nih.gov/pubmed/26468955 http://dx.doi.org/10.1371/journal.pone.0140691

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