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Comparison of 454 Ultra-Deep Sequencing and Allele-Specific Real-Time PCR with Regard to the Detection of Emerging Drug-Resistant Minor HIV-1 Variants after Antiretroviral Prophylaxis for Vertical Transmission

BACKGROUND: Pregnant HIV-infected women were screened for the development of HIV-1 drug resistance after implementation of a triple-antiretroviral transmission prophylaxis as recommended by the WHO in 2006. The study offered the opportunity to compare amplicon-based 454 ultra-deep sequencing (UDS) a...

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Detalles Bibliográficos
Autores principales:	Hauser, Andrea, Kuecherer, Claudia, Kunz, Andrea, Dabrowski, Piotr Wojtek, Radonić, Aleksandar, Nitsche, Andreas, Theuring, Stefanie, Bannert, Norbert, Sewangi, Julius, Mbezi, Paulina, Dugange, Festo, Harms, Gundel, Meixenberger, Karolin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607442/ https://www.ncbi.nlm.nih.gov/pubmed/26469189 http://dx.doi.org/10.1371/journal.pone.0140809

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