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Polyanionic Carboxyethyl Peptide Nucleic Acids (ce-PNAs): Synthesis and DNA Binding
New polyanionic modifications of polyamide nucleic acid mimics were obtained. Thymine decamers were synthesized from respective chiral α- and γ-monomers, and their enantiomeric purity was assessed. Here, we present the decamer synthesis, purification and characterization by MALDI-TOF mass spectromet...
Autores principales: | Kirillova, Yuliya, Boyarskaya, Nataliya, Dezhenkov, Andrey, Tankevich, Mariya, Prokhorov, Ivan, Varizhuk, Anna, Eremin, Sergei, Esipov, Dmitry, Smirnov, Igor, Pozmogova, Galina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607454/ https://www.ncbi.nlm.nih.gov/pubmed/26469337 http://dx.doi.org/10.1371/journal.pone.0140468 |
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