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Effect of monovalent cations on the kinetics of hypoxic conformational change of mitochondrial complex I
Mitochondrial complex I is a large, membrane-bound enzyme central to energy metabolism, and its dysfunction is implicated in cardiovascular and neurodegenerative diseases. An interesting feature of mammalian complex I is the so-called A/D transition, when the idle enzyme spontaneously converts from...
Autores principales: | Stepanova, Anna, Valls, Alba, Galkin, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Pub. Co
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607728/ https://www.ncbi.nlm.nih.gov/pubmed/26009015 http://dx.doi.org/10.1016/j.bbabio.2015.05.012 |
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