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Impacts of tissue-type plasminogen activator (tPA) on neuronal survival

Tissue-type plasminogen activator (tPA) a serine protease is constituted of five functional domains through which it interacts with different substrates, binding proteins, and receptors. In the last years, great interest has been given to the clinical relevance of targeting tPA in different diseases...

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Detalles Bibliográficos
Autores principales: Chevilley, Arnaud, Lesept, Flavie, Lenoir, Sophie, Ali, Carine, Parcq, Jérôme, Vivien, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607783/
https://www.ncbi.nlm.nih.gov/pubmed/26528141
http://dx.doi.org/10.3389/fncel.2015.00415