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Mass Spectrometric and Spectrofluorometric Studies of the Interaction of Aristolochic Acids with Proteins

Aristolochic acid (AA) is a potent carcinogen and nephrotoxin and is associated with the development of “Chinese herb nephropathy” and Balkan endemic nephropathy. Despite decades of research, the specific mechanism of the observed nephrotoxicity has remained elusive and the potential effects on prot...

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Detalles Bibliográficos
Autores principales: Li, Weiwei, Hu, Qin, Chan, Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608009/
https://www.ncbi.nlm.nih.gov/pubmed/26471474
http://dx.doi.org/10.1038/srep15192