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Structural diversity of supercoiled DNA

By regulating access to the genetic code, DNA supercoiling strongly affects DNA metabolism. Despite its importance, however, much about supercoiled DNA (positively supercoiled DNA, in particular) remains unknown. Here we use electron cryo-tomography together with biochemical analyses to investigate...

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Detalles Bibliográficos
Autores principales: Irobalieva, Rossitza N., Fogg, Jonathan M., Catanese, Daniel J., Sutthibutpong, Thana, Chen, Muyuan, Barker, Anna K., Ludtke, Steven J., Harris, Sarah A., Schmid, Michael F., Chiu, Wah, Zechiedrich, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608029/
https://www.ncbi.nlm.nih.gov/pubmed/26455586
http://dx.doi.org/10.1038/ncomms9440