PARP-1 activity is required for the reconsolidation and extinction of contextual fear memory

BACKGROUND: Memory consolidation, reconsolidation, and extinction have been shown to require new gene expression. Poly ADP-ribosylation mediated by poly (ADP-ribose) polymerase-1 (PARP-1) is known to regulate transcription through histone modification. Recent studies have suggested that PARP-1 posit...

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Detalles Bibliográficos
Autores principales: Inaba, Hiroyoshi, Tsukagoshi, Akinori, Kida, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608138/
https://www.ncbi.nlm.nih.gov/pubmed/26471780
http://dx.doi.org/10.1186/s13041-015-0153-7

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