Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts

BACKGROUND: Obesity, defined as pathologically increased body mass index (BMI), is strongly related to an increased risk for numerous common cardiovascular and metabolic diseases. It is particularly associated with insulin resistance, hyperglycemia, and systemic oxidative stress and represents the m...

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Detalles Bibliográficos
Autores principales: Homuth, Georg, Wahl, Simone, Müller, Christian, Schurmann, Claudia, Mäder, Ulrike, Blankenberg, Stefan, Carstensen, Maren, Dörr, Marcus, Endlich, Karlhans, Englbrecht, Christian, Felix, Stephan B., Gieger, Christian, Grallert, Harald, Herder, Christian, Illig, Thomas, Kruppa, Jochen, Marzi, Carola S., Mayerle, Julia, Meitinger, Thomas, Metspalu, Andres, Nauck, Matthias, Peters, Annette, Rathmann, Wolfgang, Reinmaa, Eva, Rettig, Rainer, Roden, Michael, Schillert, Arne, Schramm, Katharina, Steil, Leif, Strauch, Konstantin, Teumer, Alexander, Völzke, Henry, Wallaschofski, Henri, Wild, Philipp S., Ziegler, Andreas, Völker, Uwe, Prokisch, Holger, Zeller, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608219/
https://www.ncbi.nlm.nih.gov/pubmed/26470795
http://dx.doi.org/10.1186/s12920-015-0141-x

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