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Biological Role of Anti-aging Protein Klotho

Klotho-deficient mice have accelerated aging phenotypes, whereas overexpression of Klotho in mice extends lifespan. Klotho is an anti-aging single-pass membrane protein predominantly produced in the kidney, with shedding of the amino-terminal extracellular domain into the systemic circulation. Circu...

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Detalles Bibliográficos
Autores principales:	Kim, Ji-Hee, Hwang, Kyu-Hee, Park, Kyu-Sang, Kong, In Deok, Cha, Seung-Kuy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Yonsei University Wonju College of Medicine 2015
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608225/ https://www.ncbi.nlm.nih.gov/pubmed/26528423 http://dx.doi.org/10.15280/jlm.2015.5.1.1

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