Cargando…

Scalable and cost-effective NGS genotyping in the cloud

BACKGROUND: While next-generation sequencing (NGS) costs have plummeted in recent years, cost and complexity of computation remain substantial barriers to the use of NGS in routine clinical care. The clinical potential of NGS will not be realized until robust and routine whole genome sequencing data...

Descripción completa

Detalles Bibliográficos
Autores principales:	Souilmi, Yassine, Lancaster, Alex K., Jung, Jae-Yoon, Rizzo, Ettore, Hawkins, Jared B., Powles, Ryan, Amzazi, Saaïd, Ghazal, Hassan, Tonellato, Peter J., Wall, Dennis P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Technical Advance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608296/ https://www.ncbi.nlm.nih.gov/pubmed/26470712 http://dx.doi.org/10.1186/s12920-015-0134-9

Ejemplares similares

COSMOS: cloud enabled NGS analysis
por: Souilmi, Yassine, et al.
Publicado: (2015)

Cloud Computing for Comparative Genomics with Windows Azure Platform
por: Kim, Insik, et al.
Publicado: (2012)

Targeted capture-based NGS is superior to multiplex PCR-based NGS for hereditary BRCA1 and BRCA2 gene analysis in FFPE tumor samples
por: Zakrzewski, Falk, et al.
Publicado: (2019)

Anchoring and ordering NGS contig assemblies by population sequencing (POPSEQ)
por: Mascher, Martin, et al.
Publicado: (2013)

COSMOS: Python library for massively parallel workflows
por: Gafni, Erik, et al.
Publicado: (2014)

The cloud paradigm applied to e-Health
por: Vilaplana, Jordi, et al.
Publicado: (2013)

Validation of a high resolution NGS method for detecting spinal muscular atrophy carriers among phase 3 participants in the 1000 Genomes Project
por: Larson, Jessica L., et al.
Publicado: (2015)

Protecting genomic data analytics in the cloud: state of the art and opportunities
por: Tang, Haixu, et al.
Publicado: (2016)

Secure and scalable deduplication of horizontally partitioned health data for privacy-preserving distributed statistical computation
por: Yigzaw, Kassaye Yitbarek, et al.
Publicado: (2017)

A cloud computing based 12-lead ECG telemedicine service
por: Hsieh, Jui-chien, et al.
Publicado: (2012)

ReportFlow: an application for EEG visualization and reporting using cloud platform
por: Bertuccio, S., et al.
Publicado: (2021)

MC-GenomeKey: a multicloud system for the detection and annotation of genomic variants
por: Elshazly, Hatem, et al.
Publicado: (2017)

Technical advance in targeted NGS analysis enables identification of lung cancer risk-associated low frequency TP53, PIK3CA, and BRAF mutations in airway epithelial cells
por: Craig, Daniel J., et al.
Publicado: (2019)

Development of a scalable weight loss intervention for low-income workers through adaptation of interactive obesity treatment approach (iOTA)
por: Tabak, Rachel G., et al.
Publicado: (2018)

Real-time prediction of intradialytic relative blood volume: a proof-of-concept for integrated cloud computing infrastructure
por: Chaudhuri, Sheetal, et al.
Publicado: (2021)

Genotyping panel for assessing response to cancer chemotherapy
por: Dai, Zunyan, et al.
Publicado: (2008)

A dual fluorescent multiprobe assay for prion protein genotyping in sheep
por: Van Poucke, Mario, et al.
Publicado: (2005)

A robust, low- to medium-throughput prnp genotyping system in sheep
por: Buitkamp, Johannes, et al.
Publicado: (2004)

CYP3A4 and CYP3A5 genotyping by Pyrosequencing
por: Garsa, Adam A, et al.
Publicado: (2005)

Statistical adjustment of genotyping error in a case–control study of childhood leukaemia
por: Cooper, Matthew N, et al.
Publicado: (2012)

Gut-Lung Axis in COVID-19
por: Allali, Imane, et al.
Publicado: (2021)

The Complete Genome Sequence of Polystichum acrostichoides (Dryopteridaceae, Polypodiales)
por: Raoui, Sana, et al.
Publicado: (2022)

Sample size re-estimation in paired comparative diagnostic accuracy studies with a binary response
por: McCray, Gareth P. J., et al.
Publicado: (2017)

Stability of unfrozen whole blood DNA for remote genotypic analysis of HIV-1 coreceptor tropism
por: Meini, Genny, et al.
Publicado: (2013)

Usefulness of real time PCR for the differentiation and quantification of 652 and JP2 Actinobacillus actinomycetemcomitans genotypes in dental plaque and saliva
por: Orrù, Germano, et al.
Publicado: (2006)

High quality copy number and genotype data from FFPE samples using Molecular Inversion Probe (MIP) microarrays
por: Wang, Yuker, et al.
Publicado: (2009)

Comparison of Sanger sequencing for hepatitis C virus genotyping with a commercial line probe assay in a tertiary hospital
por: Goletti, Sylvie, et al.
Publicado: (2019)

Removing reference mapping biases using limited or no genotype data identifies allelic differences in protein binding at disease-associated loci
por: Buchkovich, Martin L., et al.
Publicado: (2015)

A method for determining haploid and triploid genotypes and their association with vascular phenotypes in Williams syndrome and 7q11.23 duplication syndrome
por: Gregory, Michael D., et al.
Publicado: (2018)

Genotyping of a tri-allelic polymorphism by a novel melting curve assay in MTHFD1L: an association study of nonsyndromic Cleft in Ireland
por: Minguzzi, Stefano, et al.
Publicado: (2012)

Multiplex pyrosequencing assay using AdvISER-MH-PYRO algorithm: a case for rapid and cost-effective genotyping analysis of prostate cancer risk-associated SNPs
por: Ambroise, Jérôme, et al.
Publicado: (2015)

A new mini-open technique of arthroscopically assisted Latarjet
por: Taverna, Ettore, et al.
Publicado: (2020)

Practicalities in running early-phase trials using the time-to-event continual reassessment method (TiTE-CRM) for interventions with long toxicity periods using two radiotherapy oncology trials as examples
por: van Werkhoven, Erik, et al.
Publicado: (2020)

Cloud computing for comparative genomics
por: Wall, Dennis P, et al.
Publicado: (2010)

Automated extraction protocol for quantification of SARS-Coronavirus RNA in serum: an evaluation study
por: Chiu, Rossa WK, et al.
Publicado: (2006)

Biomedical Cloud Computing With Amazon Web Services
por: Fusaro, Vincent A., et al.
Publicado: (2011)

Undertaking a high stakes virtual OSCE (“VOSCE”) during Covid-19
por: Blythe, Jenny, et al.
Publicado: (2021)

Magnetic resonance imaging-guided lumbar nerve root infiltrations: optimization of an in-house protocol
por: Scheffler, Max, et al.
Publicado: (2021)

Screening of exon 11 of BRCA1 gene using the high resolution melting approach for diagnosis in Moroccan breast cancer patients
por: El Khachibi, Meryam, et al.
Publicado: (2015)

A population-level strain genotyping method to study pathogen strain dynamics in human infections
por: Morgan, Sarah J., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ermtnnr7p7b20fvrhjgs5v9lvh