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Bcl-2 confers survival in cisplatin treated cervical cancer cells: circumventing cisplatin dose-dependent toxicity and resistance
BACKGROUND: Cisplatin is the main chemotherapeutic drug for the treatment of cervical cancers, however resistance to cisplatin is increasingly common and therefore has limited the efficacy and use of this drug in the clinic. Dose-dependent toxicity poses an additional challenge since patients suffer...
Autores principales: | Leisching, Gina, Loos, Benjamin, Botha, Matthys, Engelbrecht, Anna-Mart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608303/ https://www.ncbi.nlm.nih.gov/pubmed/26474854 http://dx.doi.org/10.1186/s12967-015-0689-4 |
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