Turning Spiroketals Inside Out: A Rearrangement Triggered by an Enol Ether Epoxidation

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Spiroketals organize small molecule structures into well-defined, three-dimensional configurations that make them good ligands of proteins. We recently discovered a tandem cycloisomerization–dimerization reaction of alkynyl hemiketals that delivered polycyclic, enol-ether-containing spiroketals. Her...

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Detalles Bibliográficos
Autores principales: Lorenc, Chris, Saurí, Josep, Moser, Arvin, Buevich, Alexei V, Williams, Antony J, Williamson, R Thomas, Martin, Gary E, Peczuh, Mark W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608522/
https://www.ncbi.nlm.nih.gov/pubmed/26491634
http://dx.doi.org/10.1002/open.201500122

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