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Diurnal Variation Has Effect on Differential Gene Expression Analysis in the Hippocampus of the Pilocarpine-Induced Model of Mesial Temporal Lobe Epilepsy
The molecular mechanisms underlying epileptogenesis have been widely investigated by differential gene expression approach, especially RT-qPCR methodology. However, controversial findings highlight the occurrence of unpredictable sources of variance in the experimental designs. Here, we investigated...
Autores principales: | Santos, Evelin Antonieli da Silva, Marques, Thalita Ewellyn Batista Sales, Matos, Heloísa de Carvalho, Leite, João Pereira, Garcia-Cairasco, Norberto, Paçó-Larson, Maria Luisa, Gitaí, Daniel Leite Góes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608695/ https://www.ncbi.nlm.nih.gov/pubmed/26473354 http://dx.doi.org/10.1371/journal.pone.0141121 |
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