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Naturally Occurring Deletion Mutants of the Pig-Specific, Intestinal Crypt Epithelial Cell Protein CLCA4b without Apparent Phenotype
The human CLCA4 (chloride channel regulator, calcium-activated) modulates the intestinal phenotype of cystic fibrosis (CF) patients via an as yet unknown pathway. With the generation of new porcine CF models, species-specific differences between human modifiers of CF and their porcine orthologs are...
Autores principales: | Plog, Stephanie, Klymiuk, Nikolai, Binder, Stefanie, Van Hook, Matthew J., Thoreson, Wallace B., Gruber, Achim D., Mundhenk, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608703/ https://www.ncbi.nlm.nih.gov/pubmed/26474299 http://dx.doi.org/10.1371/journal.pone.0140050 |
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