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Anti-Tumor Effects after Adoptive Transfer of IL-12 Transposon-Modified Murine Splenocytes in the OT-I-Melanoma Mouse Model
Adoptive transfer of gene modified T cells provides possible immunotherapy for patients with cancers refractory to other treatments. We have previously used the non-viral piggyBac transposon system to gene modify human T cells for potential immunotherapy. However, these previous studies utilized ado...
Autores principales: | Galvan, Daniel L., O’Neil, Richard T., Foster, Aaron E., Huye, Leslie, Bear, Adham, Rooney, Cliona M., Wilson, Matthew H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608718/ https://www.ncbi.nlm.nih.gov/pubmed/26473608 http://dx.doi.org/10.1371/journal.pone.0140744 |
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