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Accuracy and Reproducibility in Quantification of Plasma Protein Concentrations by Mass Spectrometry without the Use of Isotopic Standards
BACKGROUND: Quantitative proteomic analysis with mass spectrometry holds great promise for simultaneously quantifying proteins in various biosamples, such as human plasma. Thus far, studies addressing the reproducible measurement of endogenous protein concentrations in human plasma have focussed on...
Autores principales: | Kramer, Gertjan, Woolerton, Yvonne, van Straalen, Jan P., Vissers, Johannes P. C., Dekker, Nick, Langridge, James I., Beynon, Robert J., Speijer, Dave, Sturk, Auguste, Aerts, Johannes M. F. G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608811/ https://www.ncbi.nlm.nih.gov/pubmed/26474480 http://dx.doi.org/10.1371/journal.pone.0140097 |
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