Distinct Transcript Isoforms of the Atypical Chemokine Receptor 1 (ACKR1) / Duffy Antigen Receptor for Chemokines (DARC) Gene Are Expressed in Lymphoblasts and Altered Isoform Levels Are Associated with Genetic Ancestry and the Duffy-Null Allele

The Atypical ChemoKine Receptor 1 (ACKR1) gene, better known as Duffy Antigen Receptor for Chemokines (DARC or Duffy), is responsible for the Duffy Blood Group and plays a major role in regulating the circulating homeostatic levels of pro-inflammatory chemokines. Previous studies have shown that one...

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Detalles Bibliográficos
Autores principales: Davis, Melissa B., Walens, Andrea, Hire, Rupali, Mumin, Kauthar, Brown, Andrea M., Ford, DeJuana, Howerth, Elizabeth W., Monteil, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608815/
https://www.ncbi.nlm.nih.gov/pubmed/26473357
http://dx.doi.org/10.1371/journal.pone.0140098

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