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Risk factors for in-hospital mortality in patients starting hemodialysis
BACKGROUND: Incident hemodialysis patients have the highest mortality in the first several months after starting dialysis. This study evaluated the in-hospital mortality rate after hemodialysis initiation, as well as related risk factors. METHODS: We examined in-hospital mortality and related factor...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608878/ https://www.ncbi.nlm.nih.gov/pubmed/26484040 http://dx.doi.org/10.1016/j.krcp.2015.07.005 |
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author | Bae, Eun Hui Kim, Ha Yeon Kang, Yong Un Kim, Chang Seong Ma, Seong Kwon Kim, Soo Wan |
author_facet | Bae, Eun Hui Kim, Ha Yeon Kang, Yong Un Kim, Chang Seong Ma, Seong Kwon Kim, Soo Wan |
author_sort | Bae, Eun Hui |
collection | PubMed |
description | BACKGROUND: Incident hemodialysis patients have the highest mortality in the first several months after starting dialysis. This study evaluated the in-hospital mortality rate after hemodialysis initiation, as well as related risk factors. METHODS: We examined in-hospital mortality and related factors in 2,692 patients starting incident hemodialysis. The study population included patients with acute kidney injury, acute exacerbation of chronic kidney disease, and chronic kidney disease. To determine the parameters associated with in-hospital mortality, patients who died in hospital (nonsurvivors) were compared with those who survived (survivors). Risk factors for in-hospital mortality were determined using logistic regression analysis. RESULTS: Among all patients, 451 (16.8%) died during hospitalization. The highest risk factor for in-hospital mortality was cardiopulmonary resuscitation, followed by pneumonia, arrhythmia, hematologic malignancy, and acute kidney injury after bleeding. Albumin was not a risk factor for in-hospital mortality, whereas C-reactive protein was a risk factor. The use of vancomycin, inotropes, and a ventilator was associated with mortality, whereas elective hemodialysis with chronic kidney disease and statin use were associated with survival. The use of continuous renal replacement therapy was not associated with in-hospital mortality. CONCLUSION: Incident hemodialysis patients had high in-hospital mortality. Cardiopulmonary resuscitation, infections such as pneumonia, and the use of inotropes and a ventilator was strong risk factors for in-hospital mortality. However, elective hemodialysis for chronic kidney disease was associated with survival. |
format | Online Article Text |
id | pubmed-4608878 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-46088782015-10-19 Risk factors for in-hospital mortality in patients starting hemodialysis Bae, Eun Hui Kim, Ha Yeon Kang, Yong Un Kim, Chang Seong Ma, Seong Kwon Kim, Soo Wan Kidney Res Clin Pract Original Article BACKGROUND: Incident hemodialysis patients have the highest mortality in the first several months after starting dialysis. This study evaluated the in-hospital mortality rate after hemodialysis initiation, as well as related risk factors. METHODS: We examined in-hospital mortality and related factors in 2,692 patients starting incident hemodialysis. The study population included patients with acute kidney injury, acute exacerbation of chronic kidney disease, and chronic kidney disease. To determine the parameters associated with in-hospital mortality, patients who died in hospital (nonsurvivors) were compared with those who survived (survivors). Risk factors for in-hospital mortality were determined using logistic regression analysis. RESULTS: Among all patients, 451 (16.8%) died during hospitalization. The highest risk factor for in-hospital mortality was cardiopulmonary resuscitation, followed by pneumonia, arrhythmia, hematologic malignancy, and acute kidney injury after bleeding. Albumin was not a risk factor for in-hospital mortality, whereas C-reactive protein was a risk factor. The use of vancomycin, inotropes, and a ventilator was associated with mortality, whereas elective hemodialysis with chronic kidney disease and statin use were associated with survival. The use of continuous renal replacement therapy was not associated with in-hospital mortality. CONCLUSION: Incident hemodialysis patients had high in-hospital mortality. Cardiopulmonary resuscitation, infections such as pneumonia, and the use of inotropes and a ventilator was strong risk factors for in-hospital mortality. However, elective hemodialysis for chronic kidney disease was associated with survival. Elsevier 2015-09 2015-08-12 /pmc/articles/PMC4608878/ /pubmed/26484040 http://dx.doi.org/10.1016/j.krcp.2015.07.005 Text en Copyright © 2015. The Korean Society of Nephrology. Published by Elsevier. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Article Bae, Eun Hui Kim, Ha Yeon Kang, Yong Un Kim, Chang Seong Ma, Seong Kwon Kim, Soo Wan Risk factors for in-hospital mortality in patients starting hemodialysis |
title | Risk factors for in-hospital mortality in patients starting hemodialysis |
title_full | Risk factors for in-hospital mortality in patients starting hemodialysis |
title_fullStr | Risk factors for in-hospital mortality in patients starting hemodialysis |
title_full_unstemmed | Risk factors for in-hospital mortality in patients starting hemodialysis |
title_short | Risk factors for in-hospital mortality in patients starting hemodialysis |
title_sort | risk factors for in-hospital mortality in patients starting hemodialysis |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608878/ https://www.ncbi.nlm.nih.gov/pubmed/26484040 http://dx.doi.org/10.1016/j.krcp.2015.07.005 |
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