Sleep disorders: A review of the interface between restless legs syndrome and iron metabolism

Restless legs syndrome (RLS) is characterized by unpleasant sensations mainly in the legs. 43% of RLS-associated conditions have also been associated with systemic iron deficiency. The objective of this study was to review in the literature the relationship between iron metabolism and RLS. With an i...

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Detalles Bibliográficos
Autores principales: Daubian-Nosé, Paulo, Frank, Miriam K., Esteves, Andrea Maculano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608891/
https://www.ncbi.nlm.nih.gov/pubmed/26483934
http://dx.doi.org/10.1016/j.slsci.2014.10.002
Descripción
Sumario:Restless legs syndrome (RLS) is characterized by unpleasant sensations mainly in the legs. 43% of RLS-associated conditions have also been associated with systemic iron deficiency. The objective of this study was to review in the literature the relationship between iron metabolism and RLS. With an initial search using the keywords combination “Iron Metabolism OR Iron Deficiency AND Restless Legs Syndrome,” 145 articles were screened, and 20 articles were selected. Few studies were found for this review in the period of 2001–2014, however, the correlation between RLS and iron was evident.

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