Wnt signaling in age-related macular degeneration: human macular tissue and mouse model

BACKGROUND: The wingless-type MMTV integration site (Wnt) signaling is a group of signal transduction pathways. In canonical Wnt pathway, Wnt ligands bind to low-density lipoprotein receptor-related protein 5 or 6 (LRP5 or LRP6), resulting in phosphorylation and activation of the receptor. We hypoth...

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Detalles Bibliográficos
Autores principales: Tuo, Jingsheng, Wang, Yujuan, Cheng, Rui, Li, Yichao, Chen, Mei, Qiu, Fangfang, Qian, Haohua, Shen, Defen, Penalva, Rosana, Xu, Heping, Ma, Jian-Xing, Chan, Chi-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609061/
https://www.ncbi.nlm.nih.gov/pubmed/26476672
http://dx.doi.org/10.1186/s12967-015-0683-x

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