Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens

BACKGROUND: To determine differentially expressed and spliced RNA transcripts in chronic lymphocytic leukemia specimens a high throughput RNA-sequencing (HTS RNA-seq) analysis was performed. METHODS: Ten CLL specimens and five normal peripheral blood CD19+ B cells were analyzed by HTS RNA-seq. The l...

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Detalles Bibliográficos
Autores principales: Liao, Wei, Jordaan, Gwen, Nham, Phillipp, Phan, Ryan T., Pelegrini, Matteo, Sharma, Sanjai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609092/
https://www.ncbi.nlm.nih.gov/pubmed/26474785
http://dx.doi.org/10.1186/s12885-015-1708-9

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