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Clinical features of hepatolithiasis: analyses of multicenter-based surveys in Japan

BACKGROUND: Hepatolithiasis is a calculus disease of the liver with no known cause that is relatively uncommon, and is characterized by a refractory nature and high frequency of recurrence. Hepatolithiasis is one of the diseases listed by the Ministry of Health, Labour and Welfare of Japan under Res...

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Autores principales: Tazuma, Susumu, Nakanuma, Yasuni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609120/
https://www.ncbi.nlm.nih.gov/pubmed/26475606
http://dx.doi.org/10.1186/s12944-015-0130-2
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author Tazuma, Susumu
Nakanuma, Yasuni
author_facet Tazuma, Susumu
Nakanuma, Yasuni
author_sort Tazuma, Susumu
collection PubMed
description BACKGROUND: Hepatolithiasis is a calculus disease of the liver with no known cause that is relatively uncommon, and is characterized by a refractory nature and high frequency of recurrence. Hepatolithiasis is one of the diseases listed by the Ministry of Health, Labour and Welfare of Japan under Research on Intractable Diseases, and it requires further research on the pathogenesis as well as the therapeutic strategy. It is also included in the clinical guidelines for cholelithiasis of the Japanese Society of Gastroenterology, which suggest guiding principles for the treatment of hepatolithiasis. METHODS: we performed questionnaire surveys of hepatolithiasis twice in 2010 and in 2012. Verification of the evidence-based clinical practice guidelines a questionnaire survey of 22 facilities in 2010 and 25 facilities in 2012 across Japan that provided cooperation, which enabled us to assess 210 new cases over a two-year period. CONCLUSIONS: Comparison with two surveys that have been carried out previously revealed the main factor associated with hepatolithiasis was a history of biliary tract surgery, which was noted in the majority of cases. In addition, there was an increase of patients in whom balloon endoscopy was performed using transduodenal approach. This method is not included in the treatment options of the current clinical guidelines for cholelithiasis, so there may be a need to take it into consideration when the guidelines are revised.
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spelling pubmed-46091202015-10-18 Clinical features of hepatolithiasis: analyses of multicenter-based surveys in Japan Tazuma, Susumu Nakanuma, Yasuni Lipids Health Dis Short Report BACKGROUND: Hepatolithiasis is a calculus disease of the liver with no known cause that is relatively uncommon, and is characterized by a refractory nature and high frequency of recurrence. Hepatolithiasis is one of the diseases listed by the Ministry of Health, Labour and Welfare of Japan under Research on Intractable Diseases, and it requires further research on the pathogenesis as well as the therapeutic strategy. It is also included in the clinical guidelines for cholelithiasis of the Japanese Society of Gastroenterology, which suggest guiding principles for the treatment of hepatolithiasis. METHODS: we performed questionnaire surveys of hepatolithiasis twice in 2010 and in 2012. Verification of the evidence-based clinical practice guidelines a questionnaire survey of 22 facilities in 2010 and 25 facilities in 2012 across Japan that provided cooperation, which enabled us to assess 210 new cases over a two-year period. CONCLUSIONS: Comparison with two surveys that have been carried out previously revealed the main factor associated with hepatolithiasis was a history of biliary tract surgery, which was noted in the majority of cases. In addition, there was an increase of patients in whom balloon endoscopy was performed using transduodenal approach. This method is not included in the treatment options of the current clinical guidelines for cholelithiasis, so there may be a need to take it into consideration when the guidelines are revised. BioMed Central 2015-10-17 /pmc/articles/PMC4609120/ /pubmed/26475606 http://dx.doi.org/10.1186/s12944-015-0130-2 Text en © Tazuma and Nakanuma. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Short Report
Tazuma, Susumu
Nakanuma, Yasuni
Clinical features of hepatolithiasis: analyses of multicenter-based surveys in Japan
title Clinical features of hepatolithiasis: analyses of multicenter-based surveys in Japan
title_full Clinical features of hepatolithiasis: analyses of multicenter-based surveys in Japan
title_fullStr Clinical features of hepatolithiasis: analyses of multicenter-based surveys in Japan
title_full_unstemmed Clinical features of hepatolithiasis: analyses of multicenter-based surveys in Japan
title_short Clinical features of hepatolithiasis: analyses of multicenter-based surveys in Japan
title_sort clinical features of hepatolithiasis: analyses of multicenter-based surveys in japan
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609120/
https://www.ncbi.nlm.nih.gov/pubmed/26475606
http://dx.doi.org/10.1186/s12944-015-0130-2
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