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Renin-Angiotensin Activation and Oxidative Stress in Early Heart Failure with Preserved Ejection Fraction

Animal models have suggested a role of renin-angiotensin system (RAS) activation and subsequent cardiac oxidation in heart failure with preserved ejection fraction (HFpEF). Nevertheless, RAS blockade has failed to show efficacy in treatment of HFpEF. We evaluated the role of RAS activation and subse...

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Detalles Bibliográficos
Autores principales: Negi, Smita I., Jeong, Euy-Myoung, Shukrullah, Irfan, Veleder, Emir, Jones, Dean P., Fan, Tai-Hwang M., Varadarajan, Sudhahar, Danilov, Sergei M., Fukai, Tohru, Dudley, Samuel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609374/
https://www.ncbi.nlm.nih.gov/pubmed/26504834
http://dx.doi.org/10.1155/2015/825027