Expression of Stem Cell Markers in Preinvasive Tubal Lesions of Ovarian Carcinoma

In order to better understand the ovarian serous carcinogenic process with tubal origin, we investigated the expression of stem cell markers in premalignant tubal lesions (serous tubal intraepithelial carcinoma or STIC). We found an increased stem cell marker density in the normal fallopian tube fol...

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Detalles Bibliográficos
Autores principales: Chene, G., Ouellet, V., Rahimi, K., Barres, V., Meunier, L., De Ladurantaye, M., Provencher, D., Mes-Masson, A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609379/
https://www.ncbi.nlm.nih.gov/pubmed/26504831
http://dx.doi.org/10.1155/2015/808531
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author Chene, G.
Ouellet, V.
Rahimi, K.
Barres, V.
Meunier, L.
De Ladurantaye, M.
Provencher, D.
Mes-Masson, A. M.
author_facet Chene, G.
Ouellet, V.
Rahimi, K.
Barres, V.
Meunier, L.
De Ladurantaye, M.
Provencher, D.
Mes-Masson, A. M.
author_sort Chene, G.
collection PubMed
description In order to better understand the ovarian serous carcinogenic process with tubal origin, we investigated the expression of stem cell markers in premalignant tubal lesions (serous tubal intraepithelial carcinoma or STIC). We found an increased stem cell marker density in the normal fallopian tube followed by a high CD117 and a low ALDH and CD44 expression in STICs raising the question of the role of the stem cell markers in the serous carcinogenic process.
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spelling pubmed-46093792015-10-26 Expression of Stem Cell Markers in Preinvasive Tubal Lesions of Ovarian Carcinoma Chene, G. Ouellet, V. Rahimi, K. Barres, V. Meunier, L. De Ladurantaye, M. Provencher, D. Mes-Masson, A. M. Biomed Res Int Research Article In order to better understand the ovarian serous carcinogenic process with tubal origin, we investigated the expression of stem cell markers in premalignant tubal lesions (serous tubal intraepithelial carcinoma or STIC). We found an increased stem cell marker density in the normal fallopian tube followed by a high CD117 and a low ALDH and CD44 expression in STICs raising the question of the role of the stem cell markers in the serous carcinogenic process. Hindawi Publishing Corporation 2015 2015-10-04 /pmc/articles/PMC4609379/ /pubmed/26504831 http://dx.doi.org/10.1155/2015/808531 Text en Copyright © 2015 G. Chene et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Chene, G.
Ouellet, V.
Rahimi, K.
Barres, V.
Meunier, L.
De Ladurantaye, M.
Provencher, D.
Mes-Masson, A. M.
Expression of Stem Cell Markers in Preinvasive Tubal Lesions of Ovarian Carcinoma
title Expression of Stem Cell Markers in Preinvasive Tubal Lesions of Ovarian Carcinoma
title_full Expression of Stem Cell Markers in Preinvasive Tubal Lesions of Ovarian Carcinoma
title_fullStr Expression of Stem Cell Markers in Preinvasive Tubal Lesions of Ovarian Carcinoma
title_full_unstemmed Expression of Stem Cell Markers in Preinvasive Tubal Lesions of Ovarian Carcinoma
title_short Expression of Stem Cell Markers in Preinvasive Tubal Lesions of Ovarian Carcinoma
title_sort expression of stem cell markers in preinvasive tubal lesions of ovarian carcinoma
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609379/
https://www.ncbi.nlm.nih.gov/pubmed/26504831
http://dx.doi.org/10.1155/2015/808531
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