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Protective Effects of Cilastatin against Vancomycin-Induced Nephrotoxicity

Vancomycin is a very effective antibiotic for treatment of severe infections. However, its use in clinical practice is limited by nephrotoxicity. Cilastatin is a dehydropeptidase I inhibitor that acts on the brush border membrane of the proximal tubule to prevent accumulation of imipenem and toxicit...

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Detalles Bibliográficos
Autores principales:	Humanes, Blanca, Jado, Juan Carlos, Camaño, Sonia, López-Parra, Virginia, Torres, Ana María, Álvarez-Sala, Luís Antonio, Cercenado, Emilia, Tejedor, Alberto, Lázaro, Alberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609390/ https://www.ncbi.nlm.nih.gov/pubmed/26504822 http://dx.doi.org/10.1155/2015/704382

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