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Hemophagocytic Lymphohistiocytosis Complicating Dengue and Plasmodium vivax Coinfection

Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder. Dysfunction of cytotoxic T and natural killer (NK) cells causes uncontrolled activity of lymphocytes and histiocytes which leads to HLH. Infections, malignancies, and autoimmune disorders are associated with development of HLH. Dengue and...

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Autores principales: Khurram, Muhammad, Faheem, Muhammad, Umar, Muhammad, Yasin, Asif, Qayyum, Wajeeha, Ashraf, Amna, Zahid Khan, Javeria, Hasnain Yasir, Ali, Ansari, Yusra, Asad, Muhammad, Khan, Iram, Abbas, Shuja, Rasheed, Irum, Rasool, Natasha, Bushra Khar, Hamama Tul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609418/
https://www.ncbi.nlm.nih.gov/pubmed/26504465
http://dx.doi.org/10.1155/2015/696842
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author Khurram, Muhammad
Faheem, Muhammad
Umar, Muhammad
Yasin, Asif
Qayyum, Wajeeha
Ashraf, Amna
Zahid Khan, Javeria
Hasnain Yasir, Ali
Ansari, Yusra
Asad, Muhammad
Khan, Iram
Abbas, Shuja
Rasheed, Irum
Rasool, Natasha
Bushra Khar, Hamama Tul
author_facet Khurram, Muhammad
Faheem, Muhammad
Umar, Muhammad
Yasin, Asif
Qayyum, Wajeeha
Ashraf, Amna
Zahid Khan, Javeria
Hasnain Yasir, Ali
Ansari, Yusra
Asad, Muhammad
Khan, Iram
Abbas, Shuja
Rasheed, Irum
Rasool, Natasha
Bushra Khar, Hamama Tul
author_sort Khurram, Muhammad
collection PubMed
description Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder. Dysfunction of cytotoxic T and natural killer (NK) cells causes uncontrolled activity of lymphocytes and histiocytes which leads to HLH. Infections, malignancies, and autoimmune disorders are associated with development of HLH. Dengue and Plasmodium vivax are rare causes of HLH. We report the first ever case of a young man who developed fatal HLH that complicated Dengue Hemorrhagic Fever (DHF) and Plasmodium vivax infection.
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spelling pubmed-46094182015-10-26 Hemophagocytic Lymphohistiocytosis Complicating Dengue and Plasmodium vivax Coinfection Khurram, Muhammad Faheem, Muhammad Umar, Muhammad Yasin, Asif Qayyum, Wajeeha Ashraf, Amna Zahid Khan, Javeria Hasnain Yasir, Ali Ansari, Yusra Asad, Muhammad Khan, Iram Abbas, Shuja Rasheed, Irum Rasool, Natasha Bushra Khar, Hamama Tul Case Rep Med Case Report Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder. Dysfunction of cytotoxic T and natural killer (NK) cells causes uncontrolled activity of lymphocytes and histiocytes which leads to HLH. Infections, malignancies, and autoimmune disorders are associated with development of HLH. Dengue and Plasmodium vivax are rare causes of HLH. We report the first ever case of a young man who developed fatal HLH that complicated Dengue Hemorrhagic Fever (DHF) and Plasmodium vivax infection. Hindawi Publishing Corporation 2015 2015-10-04 /pmc/articles/PMC4609418/ /pubmed/26504465 http://dx.doi.org/10.1155/2015/696842 Text en Copyright © 2015 Muhammad Khurram et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Khurram, Muhammad
Faheem, Muhammad
Umar, Muhammad
Yasin, Asif
Qayyum, Wajeeha
Ashraf, Amna
Zahid Khan, Javeria
Hasnain Yasir, Ali
Ansari, Yusra
Asad, Muhammad
Khan, Iram
Abbas, Shuja
Rasheed, Irum
Rasool, Natasha
Bushra Khar, Hamama Tul
Hemophagocytic Lymphohistiocytosis Complicating Dengue and Plasmodium vivax Coinfection
title Hemophagocytic Lymphohistiocytosis Complicating Dengue and Plasmodium vivax Coinfection
title_full Hemophagocytic Lymphohistiocytosis Complicating Dengue and Plasmodium vivax Coinfection
title_fullStr Hemophagocytic Lymphohistiocytosis Complicating Dengue and Plasmodium vivax Coinfection
title_full_unstemmed Hemophagocytic Lymphohistiocytosis Complicating Dengue and Plasmodium vivax Coinfection
title_short Hemophagocytic Lymphohistiocytosis Complicating Dengue and Plasmodium vivax Coinfection
title_sort hemophagocytic lymphohistiocytosis complicating dengue and plasmodium vivax coinfection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609418/
https://www.ncbi.nlm.nih.gov/pubmed/26504465
http://dx.doi.org/10.1155/2015/696842
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