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A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer
Introduction. The systemic inflammatory response (SIR) plays a key role in determining nutritional status and survival of patients with cancer. A number of objective scoring systems have been shown to have prognostic value; however, their application in routine clinical practice is not clear. The ai...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609481/ https://www.ncbi.nlm.nih.gov/pubmed/26504363 http://dx.doi.org/10.1155/2015/842070 |
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author | Watt, David G. Roxburgh, Campbell S. White, Mark Chan, Juen Zhik Horgan, Paul G. McMillan, Donald C. |
author_facet | Watt, David G. Roxburgh, Campbell S. White, Mark Chan, Juen Zhik Horgan, Paul G. McMillan, Donald C. |
author_sort | Watt, David G. |
collection | PubMed |
description | Introduction. The systemic inflammatory response (SIR) plays a key role in determining nutritional status and survival of patients with cancer. A number of objective scoring systems have been shown to have prognostic value; however, their application in routine clinical practice is not clear. The aim of the present survey was to examine the range of opinions internationally on the routine use of these scoring systems. Methods. An online survey was distributed to a target group consisting of individuals worldwide who have reported an interest in systemic inflammation in patients with cancer. Results. Of those invited by the survey (n = 238), 65% routinely measured the SIR, mainly for research and prognostication purposes and clinically for allocation of adjuvant therapy or palliative chemotherapy. 40% reported that they currently used the Glasgow Prognostic Score/modified Glasgow Prognostic Score (GPS/mGPS) and 81% reported that a measure of systemic inflammation should be incorporated into clinical guidelines, such as the definition of cachexia. Conclusions. The majority of respondents routinely measured the SIR in patients with cancer, mainly using the GPS/mGPS for research and prognostication purposes. The majority reported that a measure of the SIR should be adopted into clinical guidelines. |
format | Online Article Text |
id | pubmed-4609481 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-46094812015-10-26 A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer Watt, David G. Roxburgh, Campbell S. White, Mark Chan, Juen Zhik Horgan, Paul G. McMillan, Donald C. Mediators Inflamm Research Article Introduction. The systemic inflammatory response (SIR) plays a key role in determining nutritional status and survival of patients with cancer. A number of objective scoring systems have been shown to have prognostic value; however, their application in routine clinical practice is not clear. The aim of the present survey was to examine the range of opinions internationally on the routine use of these scoring systems. Methods. An online survey was distributed to a target group consisting of individuals worldwide who have reported an interest in systemic inflammation in patients with cancer. Results. Of those invited by the survey (n = 238), 65% routinely measured the SIR, mainly for research and prognostication purposes and clinically for allocation of adjuvant therapy or palliative chemotherapy. 40% reported that they currently used the Glasgow Prognostic Score/modified Glasgow Prognostic Score (GPS/mGPS) and 81% reported that a measure of systemic inflammation should be incorporated into clinical guidelines, such as the definition of cachexia. Conclusions. The majority of respondents routinely measured the SIR in patients with cancer, mainly using the GPS/mGPS for research and prognostication purposes. The majority reported that a measure of the SIR should be adopted into clinical guidelines. Hindawi Publishing Corporation 2015 2015-10-04 /pmc/articles/PMC4609481/ /pubmed/26504363 http://dx.doi.org/10.1155/2015/842070 Text en Copyright © 2015 David G. Watt et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Watt, David G. Roxburgh, Campbell S. White, Mark Chan, Juen Zhik Horgan, Paul G. McMillan, Donald C. A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer |
title | A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer |
title_full | A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer |
title_fullStr | A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer |
title_full_unstemmed | A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer |
title_short | A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer |
title_sort | survey of attitudes towards the clinical application of systemic inflammation based prognostic scores in cancer |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609481/ https://www.ncbi.nlm.nih.gov/pubmed/26504363 http://dx.doi.org/10.1155/2015/842070 |
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