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Lung Epithelial TRPA1 Transduces the Extracellular ROS into Transcriptional Regulation of Lung Inflammation Induced by Cigarette Smoke: The Role of Influxed Ca(2+)

The mechanism underlying the inflammatory role of TRPA1 in lung epithelial cells (LECs) remains unclear. Here, we show that cigarette smoke extract (CSE) sequentially induced several events in LECs. The Ca(2+) influx was prevented by decreasing extracellular reactive oxygen species (ROS) with the sc...

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Detalles Bibliográficos
Autores principales:	Lin, An-Hsuan, Liu, Meng-Han, Ko, Hsin-Kuo, Perng, Diahn-Warng, Lee, Tzong-Shyuan, Kou, Yu Ru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609484/ https://www.ncbi.nlm.nih.gov/pubmed/26504357 http://dx.doi.org/10.1155/2015/148367

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