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Macrophage-Targeting Gene Delivery Using a Micelle Composed of Mannose-Modified Lipid with Triazole Ring and Dioleoyl Trimethylammonium Propane

Gene carriers with cell specific ligand molecules are needed for the treatment of several diseases. Mannose is known to be recognized and incorporated into the cells through mannose recognition lectins that are exclusively expressed on macrophages. In this study, we synthesized two types of mannose-...

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Detalles Bibliográficos
Autores principales: Fukuda, Ichiki, Mochizuki, Shinichi, Sakurai, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609769/
https://www.ncbi.nlm.nih.gov/pubmed/26509149
http://dx.doi.org/10.1155/2015/350580