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Epigenetic Regulation of Werner Syndrome Gene in Age-Related Cataract
Purpose. To examine the promoter methylation and histone modification of WRN (Werner syndrome gene), a DNA repair gene, and their relationship with the gene expression in age-related cataract (ARC) lens. Methods. We collected the lenses after cataract surgery from 117ARC patients and 39 age-matched...
Autores principales: | Zhu, Xi, Zhang, Guowei, Kang, Lihua, Guan, Huaijin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609838/ https://www.ncbi.nlm.nih.gov/pubmed/26509079 http://dx.doi.org/10.1155/2015/579695 |
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