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Epigenetic Regulation of Werner Syndrome Gene in Age-Related Cataract

Purpose. To examine the promoter methylation and histone modification of WRN (Werner syndrome gene), a DNA repair gene, and their relationship with the gene expression in age-related cataract (ARC) lens. Methods. We collected the lenses after cataract surgery from 117ARC patients and 39 age-matched...

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Detalles Bibliográficos
Autores principales: Zhu, Xi, Zhang, Guowei, Kang, Lihua, Guan, Huaijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609838/
https://www.ncbi.nlm.nih.gov/pubmed/26509079
http://dx.doi.org/10.1155/2015/579695

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